AppA Server

Structure 1cz8: VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH AN AFFINITY MATURED ANTIBODY

Heavy chain: blue color; Antigen: salmon color; Interfacial waters: red balls; Contact residues: shown in sticks

Number of contact residues of heavy chain = 3

Contact residues of heavy chain have 0 Hbonds, 0 hydrophobic, 2 vdW, 0 ionic interactions with antigen, and 1 Hbonds with interfacial waters

No.	Contact Residues of Heavy Chain	Region Chothia	Secondary Structure	Solvent Accessibility	Number of Hbonds with Antigen	Number of Hydrophobic Interactions	Number of VdW Interactions	Number of Ionic Interactions	Number of Hbonds with Interfacial Waters
1	HIS H 31	CDR-H1	Strand	Exposed	0	0	2	0	0
2	TYR H 54	CDR-H2	Coil	Exposed	0	0	0	0	1
3	TYR H 101	CDR-H3	Coil	Exposed	0	0	0	0	0


Interactions of contact residues of heavy chain		Structure of contact residues of heavy chain		Detailed contact residues of heavy chain

Number of contact residues of antigen = 3

Contact residues of antigen have 0 Hbonds, 0 hydrophobic, 2 vdW, 0 ionic interactions with antibody, and 1 Hbonds with interfacial waters

No.	Contact Residues of Antigen	Secondary Structure	Solvent Accessibility	Number of Hbonds with Antibody	Number of Hydrophobic Interactions	Number of VdW Interactions	Number of Ionic Interactions	Number of Hbonds with Interfacial Waters
1	VAL V 14	Coil	Exposed	0	0	0	0	0
2	PHE V 17	Helix	Exposed	0	0	2	0	0
3	TYR V 21	Helix	Exposed	0	0	0	0	1


Interactions of contact residues of antigen		Structure of contact residues of antigen		Detailed contact residues of antigen

Number of interfacial waters = 1

No.	Interfacial Waters	Number of Hbonds with Heavy Chain	Number of Hbonds with Antigen	Number of Hbonds with Other Interfacial Waters
1	HOH H 509	1	1	0


Hbonds of interfacial water molecules		Structure of interfacial water molecules		[back to top]